![]() Example RPG Game Information: Information on running, building, or scripting the example RPG game.Models: How to put models into the game.Editing Reference: Map making reference.Editing Tutorial: A guide to making maps.Config: How to run the game, configure it for your machine, and extend it with scripts.You will want to read (roughly this order): The source code for the engine used in these games is Open Source (ZLIB licence, read the "License" section below carefully before starting ANY kind of project based on this engine). If your question isn't answered there, you can try posting to a relevant thread, or creating your own, being sure to supply a good description of your problem, and your operating system/hardware/software setup, while refraining from wild accusations.Ĭube 2: Sauerbraten is a multiplayer/singleplayer FPS freeware game project. Cube Forums: If after reading the documentation and wiki you still have any questions, you can try searching the forums.Sauerbraten IRC Channel: Online public chat with Cube developers, supporters and fans, via the QuakeNet IRC Network.Quadropolis: Online Cube Engine community, with user made maps, mods, and scripts.Cube 2: Sauerbraten: The Sauerbraten FPS (First Person Shooter) Homepage.Cube and Cube 2 Engines: Start Page for the Cube Engine series.Here are some places of interest on the internet, which are related to Cube / Cube 2: Sauerbraten. ![]() ![]() First of all, welcome to Cube 2: Sauerbraten! To start off, if you are looking for help with the game itself, refer to the Documentation below. ![]()
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![]() ![]() All apes lack tails as they are not needed for balancing. The two bones (ulna and radius) in the lower fore limb and the two bones (tibia and fibula) in lower hind limb of apes are separate and highly mobile. Apes have extremely flexible shoulders, elbows and wrists. ![]() Apes’ fore limbs are longer than their hind limbs (except for humans). The development of a vertical posture in apes was accompanied by increased manual dexterity. These features are related to the upright posture of their bodies. The length of spine between rib cage and pelvis is much shorter in apes than in monkeys. While apes occur only in tropical or subtropical regions of the Old World, namely Africa and Asia, humans live in all regions of the world.Īs so much information about apes and humans is readily and easily available from other sources, including the World Wide Web, this page on apes has been planned only to illustrate our ape skulls and skeletons so they can be compared to the skulls and skeletons of the other animals in our Collections.Īs the skeleton of a chimpanzee (1) and gibbon (2) to the right show, apes have short backs with wide, barrel-shaped chests and robust pelvic girdles. This website follows the scheme whereby modern humans, Homo sapiens, are assigned to the family Hominidae with the apes. The apes are humans’ closest relatives but the place of humans in the classification schemes of apes is controversial. The family Hominidae comprises the great apes - orang utans, chimpanzees, bonobos, gorillas.The family Hylobatidae comprises the lesser apes - gibbons and siamangs, which are highly adapted to an arboreal existence.Within the infraorder Catarrhini, apes and humans are assigned to two families in the superfamily Hominoidea. The name catarrhine literally means ‘drooping nose’. SUBORDER HAPLORHINI INFRAORDER CATARRHINI SUPERFAMILY HOMINOIDEA APES AND HUMANSĪpes are grouped together with Old World monkeys in the infra-order Catarrhini because their nostrils are narrow and close together. ![]() ![]() ![]() Its versatility enables effortless integration into workflows for managing countless tasks, including but not limited to, document creation, budgeting, personal finance, tax record management, small business document management, student/research analysis, and extensive needs of government agencies, non-profit organizations, and largest corporations on the planet.Įven though it is filled to the brim with tools and services, the user interface of the MSExcel is as intuitive as ever, providing easy access to every one of its functions via tabbed toolbars on the top of the window, right-click cell menus, and powerful configuration tools in the main setting window. While it may not be the easiest software to learn, it can offer significant benefits for users who need to analyze and manage data on a regular basis. Overall, MS Excel is a powerful and versatile spreadsheet software for Windows 11/10 that can be used for a wide range of applications. There is a steep learning curve, and users may need to invest significant time and effort to master the software's features and capabilities. However, it can also be quite complex and overwhelming for beginners, especially those who are not familiar with spreadsheet concepts and formulas. Additionally, Excel offers robust collaboration features, allowing users to share and co-author spreadsheets in real-time, awesome! It also integrates well with other Microsoft Office applications, such as Word and PowerPoint, which can be useful for creating reports and presentations based on Excel data. Users can create and format spreadsheets to meet their specific needs, and can also use macros and add-ins to automate repetitive tasks and extend the software's functionality. One of the strengths of Excel is its flexibility and customization options. It offers a wide range of features and tools that can help users organize and analyze data, create charts and graphs, and automate tasks. Microsoft Excel is a powerful spreadsheet desktop app that is widely used for various purposes, including data analysis, financial modeling, and project management. Regarded as the gold standard for spreadsheet creation and analysis, Excel Home and Student to this day outmatches all competition with its wide array of tools and powerful advanced features that satisfy the needs of everyone, from first-time spreadsheet users to largest corporations who are interested in analytics and integrated forecasting functions. It is very hard to quickly review software so powerful, versatile, ubiquitous, and genre-defining as MS Excel. Since 1990, Excel can be found as a part of the Microsoft Office, a suite of document, presentation, and email editing applications covering all usage scenarios needed in a modern collaborative working environment. Is a one-time purchase (currently for $9.Buy Microsoft 365 for only $6.99/month - Powerful Productivity Apps! Use Word, Excel, PowerPoint and More to collaborate in real time or work offline.Īvailable today on all modern platforms, including Windows, macOS, Android, and iOS, today this app is used by hundreds of millions of people each day.The Microsoft Office software available from OnTheHub The license to use the software expires when the west campus employee is no longer active. Can be installed on up to 5 devices, even mobile ( Find out what devices you have Office installations on and how to deactivate them if you reach this quota)Īctive west campus employees** can purchase Microsoft Office downloads for a discounted rate from OnTheHub, and OnTheHub provides an activation key.Is a subscription service, and thus Office365-acquired applications are continually checking that your account is active.The license to use the software expires when the student or west campus employee is no longer active. ![]() The software is activated through an active Stony Brook University Office 365 subscription. Office 365Īctive students* and active west campus employees** can directly download and install Microsoft Office software from Office 365 on up to five devices (installation instructions for Windows and Mac). Managed machines (computers managed by the University) will already have Office installed. Depending on your status on campus and your needs, you can acquire Microsoft Office media and software activation/keys from the options listed below. Stony Brook University's license with Microsoft gives active students* and active west campus employees** rights to use the software, this includes 1) license, 2) media, and 3) software activation/keys. ![]() ![]() ![]() Unravelling the dynamic behavior of the TCR repertoire during ICT will be highly valuable for tracking and understanding anti-tumor immunity, biomarker discovery, and ultimately for the development of novel strategies to improve patient outcomes. The field of immuno-sequencing is rapidly developing and cross-disciplinary efforts are required to maximize the analysis, application, and validation of sequencing data. ![]() Single-cell sequencing is a breakthrough technology that can link phenotype with specificity, identifying T cell clones that are crucial for successful ICT. Discovery of predictive biomarkers could lie in novel analysis approaches, such as network analysis of amino acids similarities between TCR sequences. We discuss the advantages and limitations of current metrics used to characterize and represent TCR repertoire diversity. We will also explore how changes to the repertoire in different anatomical locations can better correlate and perhaps predict treatment outcome. Here, we review how the repertoire influences response to ICT and conversely how ICT affects repertoire diversity. T cell receptor (TCR) sequencing allows for sensitive tracking of dynamic changes in antigen-specific T cells at the clonal level, giving unprecedented insight into the mechanisms by which ICT alters T cell responses. T cell repertoires can be comprehensively profiled by high-throughput sequencing at the bulk and single-cell level. The specificity of adaptive immune cells, such as T and B cells, is determined by antigen-specific receptors. ICT primarily acts at the level of adaptive immunity. ![]() Understanding immune mechanisms that underlie responsiveness to ICT will help identify predictive biomarkers of response and develop treatments to convert non-responding patients to responding ones. However, the majority of treated patients do not respond. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. Immunotherapies have revolutionized cancer treatment. 6School of Medicine, University of Western Australia, Perth, WA, Australia.5Canada’s Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.4Telethon Kids Institute, Perth, WA, Australia.3Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia.2School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.1National Centre for Asbestos Related Diseases, Institute of Respiratory Health, University of Western Australia, Perth, WA, Australia.Nowak 1,6, Willem Joost Lesterhuis 1,2,4, Richard A. Joel Kidman 1,2, Nicola Principe 1,2, Mark Watson 3, Timo Lassmann 4, Robert A. Clonal Diversity of Memory CD8 + T Cell Subsets Might Offer a Dynamic Biomarker of ICT Response.Moving Beyond Diversity: Novel Approaches to Study TCR Repertoires.Improving How TCR Repertoire Data is Represented.Expansion of Intra-Tumoral TCR Clonotypes is a Feature of Response to Anti-PD-1 Therapy.Nuanced Analysis of PD-1 + Blood T Cells Might Offer a Biomarker to Response to PD-1/L1 Blockade.Anti-CTLA-4 Drives Clonal Expansion of Tumor Infiltrating Lymphocytes.Anti-CTLA-4 Monotherapy Remodels the Blood TCR Repertoire.TCR Repertoires Can be Characterized by Different Metrics.Sequencing Technology Is Important for the Characterization of TCR Repertoires.Measurements of Dynamic Change in the Immune System Could Offer a Biomarker of ICT Response.ICT is a Revolutionary Cancer Therapy, but Not All Patients Respond.Jude Children's Research Hospital, United States TABLE OF CONTENTS ![]() ![]() ![]() You can turn that feature off if you find it irritating too. You may sometimes have to rotate it a few times, but it kicks in eventually. The ereader will also automatically adjust to suit landscape or portrait orientation. The buttons on the bezel of the device make it easy to flick through pages quickly. The Kobo Forma may not have an all-metal design, but it's comfortable to hold when you're reading and you'll find the display clear enough to read a variety of books comfortably. Pros Crisp, large display Display lighting adjusts. ![]() It's worth noting that the Kobo Forma is also waterproof, so you can read this in the bath or at a beach without worrying about damaging it from a splash of water. Kobo Forma MSRP 279.99 Score Details DT Editors' Choice It’s pricey, but the Kobo Forma comes close to being the perfect ebook reader. It may just be less ideal for those who want to read graphic novels or comics. The display here is E Ink, so everything you read will be in black and white but the picture is clear enough for the average book. The touchscreen itself was as speedy as you’d expect from an ereader and responsive enough, but we just find the buttons a touch easier than swiping the display. With a lightweight and ergonomic design, an 8. ADE is only compatible with Kobo eReaders and will not work with your Kobo App.On the edge where you’ll grasp the device you’ll find two large buttons for cycling through pages, which we found easier to use than the touchscreen. Kobo Forma offers you the ultimate reading experience.You can read social DRM files without using ADE. If you download a book that is protected with Adobe DRM, you will need to use Adobe Digital Editions to put it on your eReader. 29.99 Buy Now Learn More > Kobo Clara 2E Basic SleepCover - Deep Ocean Blue 19.99 Buy Now Learn More > Kobo Clara HD SleepCover 29.99 Buy Now Learn More > Kobo Nia SleepCover 19.Your eReader supports Adobe DRM and Social DRM.DRM protects books from unauthorized copying, and is often used by libraries, publishers, and booksellers. EPUB or PDF books with an ACSM file extension are protected by Digital Rights Management (DRM).A single battery charge can last for weeks. Read in the sun on its glare-free 6 touchscreen, or read at night thanks to adjustable ComfortLight. With 8GB of storage, you can carry up to 6,000 eBooks. ![]() Books with audio or video content: ePub3AV 109.99 FREE Delivery Kobo Nia is our friendliest eReader yet. ![]()
![]() McConaughey's career certainly reached it's prime, when he played HIV carrier Ron Woodroof in the biographical drama Dallas Buyers Club (2013), shot in less than a month. After this performance that was considered one of his best until then, Matthew played other iconic characters as district attorney Danny Buck Davidson in Bernie (2011), the wild private detective "Killer" Joe Cooper in Killer Joe (2011), Mud in Mud (2012), reporter Ward Jensen in The Paperboy (2012), male stripper club owner Dallas in Magic Mike (2012), starring Channing Tatum. That change came in 2011, in his first movie after that pause, when he portrayed criminal defense attorney Mickey Haller in The Lincoln Lawyer (2011), that operates mostly from the back seat of his Lincoln car. Since 2010, he has moved away from romantic comedies. After playing Connor Mead in Ghosts of Girlfriends Past (2009), co-starring with Jennifer Garner, McConaughey took a two year hiatus to open different opportunities in his career. In 2008, he played treasure hunter Benjamin "Finn" Finnegan in Fool's Gold (2008), again with Kate Hudson. In 2006, he starred in the romantic comedy Failure to Launch (2006), and later as head coach Jack Lengyel in We Are Marshall (2006), along with Matthew Fox. He played Denton Van Zan, an American warrior and dragons hunter in the futuristic thriller Reign of Fire (2002), where he co-starred with Christian Bale. In the 2000s, he became known for starring in romantic comedies, such as The Wedding Planner (2001), opposite Jennifer Lopez, and How to Lose a Guy in 10 Days (2003), in which he co-starred with Kate Hudson. Tyler, in a WW II story of the daring mission of American submariners trying to capture the Enigma cipher machine. In 1999, he starred in the comedy Edtv (1999), about the rise of reality television, and in 2000, he headlined Jonathan Mostow's U-571 (2000), portraying officer Lt. During this time, he also wrote, directed and starred in the 20-minute short The Rebel (1998). ![]() In 1998, he teamed again with Richard Linklater as one of the bank-robbing brothers in The Newton Boys (1998), set in Matthew's birthplace, Uvalde, Texas. Science Carl Sagan) and Steven Spielberg's Amistad (1997), a fact-based 1839 story about the rebellious African slaves. His following performances were Robert Zemeckis' Contact (1997) with Jodie Foster (the film was finished just before the death of the great astronomer and popularizer of space The actor was soon being hailed as one of the industry's hottest young leading man inspiring comparisons to actor Paul Newman. ![]() Shortly thereafter, moving to L.A., Matthew became a sensation with his performances in two high-profile 1996 films Lone Star (1996), where he portrayed killing suspected sheriff and in the film adaptation of John Grisham's novel A Time to Kill (1996), where he played an idealistic young lawyer opposite Sandra Bullock and Kevin Spacey. Texas Chainsaw Massacre: The Next Generation (1995), playing a mad bloodthirsty sadistic killer, opposite Renée Zellweger. His character was initially in three scenes but the role grew to more than 300 lines as Linklater encouraged him to do some improvisations. At first, Linklater thought Matthew was too handsome to play the role of a guy chasing high school girls in his coming-of-age drama Dazed and Confused (1993), but cast him after Matthew grew out his hair and mustache. Once, in his hotel bar in Austin, he met the casting director and producer Don Phillips, who introduced him to director Richard Linklater for his next project. He began his acting career in 1991, appearing in student films and commercials in Texas and directed short films as Chicano Chariots (1992). But, when he discovered an inspirational Og Mandino book "The Greatest Salesman in the World" before one of his final exams, he suddenly knew he had to change his major from law to film. Back to the States, he attended the University of Texas in Austin, originally wishing to be a lawyer. Showing little interest in his father's oil business, which his two brothers later joined, Matthew was longing for a change of scenery, and spent a year in Australia, washing dishes and shoveling chicken manure. ![]() Matthew grew up in Longview, Texas, where he graduated from the local High School (1988). He is of Irish, Scottish, German, English, and Swedish descent. His father, James Donald McConaughey, was a Mississippi-born gas station owner who ran an oil pipe supply business. His mother, Mary Kathleen (McCabe), is a substitute school teacher originally from New Jersey. American actor and producer Matthew David McConaughey was born in Uvalde, Texas. ![]() ![]() ![]() Since the recent Firefox updates, my RoboForm toolbar no longer works. I've also been using RoboForm as my password manager for a much longer time. I've been using Firefox for a very long time. So I'm submitting this same question here, hoping someone can help! Editor: fix keys in search box: Home/End first/last position, Ctrl+Home/End: first/last item.ĭownload: RoboForm 7.9.11.1 | 15.I submitted the following question as FEEDBACK online on 11/06/15, but have not heard back from anyone in support at Firefox.Editor: add shortcuts: Ctrl+Backspace to delete a word back, Ctrl+Delete to delete a next word.Firefox 33+, RF2Go: fix RF2Go does not attach to Firefox 33 and later.Firefox: fix RF does not install extension into Firefox ESR.Firefox: fix RF may fail to detect Firefox installtion in some cases.Chrome + High DPI Screen: fix texts are too small in RF dropdown menus.Chrome 38+: fix RF does not install Chrome extension if it was previously removed via Chrome->Settings.Chrome: fix clicking on Minimize button in Chrome can trigger AutoSave in BA window.Fix RF extension is not added to Yandex browser if Google Chrome is not installed.Chrome + Basic Auth: fix not showing AutoSave for Basic Auth.Chrome + Basic Auth: fix crash when BA window appears on site with invalid cert.Chrome + Basic Auth: fix not attaching to basic auth window in some 2-window cases.Fix some random crashes related to closing of RF popup windows.Installer: increase waiting time before showing Force Close buttons.Installer: fix RF installer shows too big icon for Chrome 64 bit on Close Applications.Sync: OpenSSL upgraded to 1.0.1j, to fix recently vulnerabilities such as Poodle.Add 'RoboForm > Sync > Manage RoboForm Everywhere Account' command to RoboForm menu.Sync: fix One Time Password did not work, if WinInet option is used.Sync: do not require One Time Password for background syncing of usage info.Sync: fix not including some files into sync due to include.PDA-friendly: Sync your passwords to Pocket PC and Palm.Ideal: IE 7 and Vista are fully supported.Universal: works with Internet Explorer, AOL/MSN, Firefox.Robust: Works with Internet Explorer, AOL, MSN, and other browsers.Phone-friendly: sync your passwords to Windows Mobile and Palm.Portable: RoboForm2Go runs from a USB flash drive.Complete: Synchronize passwords between computers using GoodSync.Thoughtful: Back up your passwords and copy them between computers.Perfect: Defeat Keyloggers by not using the keyboard to type passwords.Powerful: Fight Phishing by entering passwords only on matching web sites.Smart: Generate random passwords to maximize password strength.Secure: Encrypts your passwords, fights Phishing, and defeats Keyloggers.Strong: Generates random passwords to protect you against hackers.Saves Time: Fills long registration and checkout forms with one click.Easy: Automatically memorizes your passwords and logs you into websites.Roboform manages your passwords and fills forms with one click! Roboform is… The all new RoboForm 7 comes with Chrome and Safari browser support, iPhone/iPad and Android support, as well a brand new RoboForm Everywhere license for use on unlimited computers and mobile devices. RoboForm uses strong AES encryption for complete data security. This allows you to use stronger passwords, making your online experience more secure. You remember one Master Password, and RoboForm remembers the rest. You no longer need to remember all your passwords. Simply click on your RoboForm Identity and RoboForm fills-in the entire form for you. With just one click RoboForm will navigate to a Web site, enter your username and password and click the submit button for you.Ĭompleting long registration or checkout forms is also a breeze. RoboForm's powerful Logins feature eliminates the manual steps of logging into any online account. RoboForm memorizes and securely stores each user name and password the first time you log into a site, then automatically supplies them when you return. ![]() RoboForm makes logging into Web sites and filling forms faster, easier, and more secure. RoboForm is the top-rated Password Manager and Web Form Filler that completely automates password entering and form filling. ![]() ![]() The vibes are immaculate," Panthers cornerback Donte Jackson said at the end of minicamp. Carolina then hosts the Saints in Week 2, so back-to-back division games at the outset will set the tone for which team might be the squad to beat in the upcoming season, though all four teams having at least one new coordinator will make them all works in progress. Young and Ridder will open the 2023 season against each other, with the Panthers traveling to Atlanta to face the Falcons. Atlanta is going with second-year pro Desmond Ridder, who took over for the final four games of his rookie season but like Young is a young passer trying to lead a veteran team. Tom Brady retired in Tampa, so either Baker Mayfield or Kyle Trask takes over there, and the Saints brought in Derek Carr as the new starter. Reich is the only new coach in the division, but all four teams are making adjustments at quarterback. The challenge of installing and implementing new schemes this summer has brought with it a bonding aspect among players helping each other through the same learning curve.Ĭarolina is in a tightly packed NFC South, where one win separated defending champion Tampa Bay from last place and three teams tied with a 7-10 record. ![]() It helps Young that everyone around him is also learning a new offense from coordinator Thomas Brown and a new defense from Ejiro Evero, a new way of approaching football from head coach Frank Reich. … Them embracing me and all the rookies, all the free agents, all the guys that are new here - it's a new group, but it doesn't feel like it in the locker room. "There's a lot of guys here that have had a lot of success and played a lot of snaps of NFL football. ![]() "Being embraced by the locker room, that means a lot to me," Young said last week as the Panthers finished their mandatory minicamp as the last work before they reconvene late next month for training camp and the 2023 season. The 21-year-old has also shown how grateful he is for the way his new team has welcomed him. The former Alabama standout and Heisman Trophy winner has been on the job fewer than two months, but despite the presence of a solid veteran in Andy Dalton, Young is already getting a starter's reps, showing he's ready to lead the team from his first game. 1 overall draft pick, it is very much handing him the keys to the franchise, but that inevitable transition has come quickly and smoothly with Bryce Young and the Carolina Panthers. When a team takes a quarterback with a No. ![]() ![]() ![]() May be one of the reasons why Reptiles Are Abhorrent-note that lizards and turtles, two groups that include herbivores, get to be protagonists more often than snakes and crocodilians, which are all predators. In-universe might explain the Xenophobic Herbivore. Goes hand-in-hand with Super-Persistent Predator, Herbivores Are Friendly, Scavengers Are Scum. Can overlap with Humans Are the Real Monsters, and maybe even Humans Are Cthulhu (particularly in Xenofiction). Often seen in conjunction with Carnivore Confusion. Subtrope of Good Animals, Evil Animals and Always Chaotic Evil. There are still a few ways to avoid this though, the most famous being with the fish-eating characters who are often spared sympathy thanks to their targets being non-sapient (see No Cartoon Fish for more about that trope). The more anthropomorphic they are shown to be the more likely they are to overhunt. Sapient Eat Sapient is a justified case of this, since there are sapient predators that know what they are doing and sapient prey that has a right to live. When the story focuses on a prey animal, there's not a lot of ways to keep predators from being monstrous. On the other hand, to the mouse, what the owl is like inside isn't as relevant as that it's trying to eat you. This trope may be one of The Oldest Ones in the Book, despite predators serving a vital ecological role (no apex predators=too many herbivores=ecosystem completely collapses), or needing to eat meat to live. This is a common way to deal with predators in talking animal fiction like World of Mammals or World of Funny Animals. (Sometimes, their prey actually defeats them!). In works involving talking animals, carnivores almost always fail to catch their prey. And even if the main character is a dog, that is the Villain Protagonist at best. For instance, if the heroes are mice, often Cats Are Mean if the main character is a squirrel, then Dogs Hate Squirrels. The predator's desire to eat the prey makes the predator a villain, or at least, a Designated Villain. In fiction, particularly if the prey can talk, carnivores are often evil, and all the heroes are herbivores. ![]() ![]()
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